Kawasaki's Disease: experience in our hospital

Abstract

Objective: The aim of this study was to analyze the incidence and clinical spectrum of Kawasaki’s disease in children attended in our hospital.
Patients and methods: Retrospective review of all children with Kawasaki’s disease evaluated in the department of Pediatric of Hospital Central (Asturias), between 1995 and 2007.
Results: Nineteen patients with Kawasaki’s disease were analyzed. 84% were younger than 3 years and 57% men. The annual incidence rate in our health area was estimated at 8.4 cases per 100,000 children < 5 years. 31 % (all male) showed abnormalities in the initial echocardiography, none that included coronary aneurysms, all them were normalized in later controls. Blood analysis showed alterations of high ESR (77% of cases) and C-reactive protein (75%). Only 2 children did not respond to IV gammaglobulin requiring a second dose.
Conclusions: The annual incidence rate for Kawasaki’s disease in our area was similar to that in Europe and the United States. Coronary aneurysms were more common in men and in patients with prolonged fever.