Prevalence of pneumococcal meningitis in the province of Salamanca

Abstract

Pneumococcal meningitis, globally have decreased since heptavalent conjugate vaccine was introduced. However, cases due to nonvaccine serotypes have increased. Object: To know the prevalence of pneumococcal meningitis in our province and the evolution during last years. Methods: Prospective study of pneumococcal meningitis admitted in the University Hospital of Salamanca during 2003 to 2008. Results: Five cases of meningitis were recorded. Annual prevalence was estimated at 6 per 100.000 children < 5 years. Serotypes isolated were 7F in three patients and one 19A. Prevalence rate during first 3 years compared to last 3 years rised up to 32%. Conclusions: Nowdays, pneumococcal meningitis in our province are due to nonvaccine serotypes, especially to 7F and 19A. During last years incidence rates of these was increased.