How to Cite
1.
Álvarez Granda L, Ocio G, Lozano M, González Martínez-Pedrayo A, García Fuentes M. Neonatal screening of alpha-1 antitrypsin deficiency in Cantabria. Bol Pediatr. 1988;29(129):261-267. doi:10.63788/07804b84
Abstract
A pilot study on neonatal screening of alpha-1 antitrypsin deficiency was carried out in 3.270 newborns from Cantabria, between June and December 1985. That represents more than 90 % of newborns during that period. The method is based in comparing alpha-1 antitrypsin to transferrin levels. The authors used an electroimmunodiffusion of dried samples got from phenilcetonuria neonatal screening. Six deficient children (2 Pi Z and 4 Pi SZ) were detected. None of them presented neonatal cholestasis; on the contrary all children showed clinical and analytical normality at 1 year of age.
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Copyright (c) 1988 Boletín de Pediatría