Cardiacal participation in perinatal hypoxia

Abstract

With the purpose of detecting cardiacal symptoms in perinatal hypoxia, the perinatal antecedents, clinical, radiological, electrocardiographic, echocardiographic and enzimatic findings have been estudied in 29 newborns. With the combined data of all of them, six newborns (20,68%) were diagnosed with transient myocardial ischemia. The most frequent clinical findings were cyanosis (50%), bradicardia (50%) and radiological cardiomegaly (66,66%). The electrocardiographic ischemic signs were significantly more frequent (p <0.05) in the newborns with cardiacal symptoms (83.33%) than in the newborns without these (52.17%), in all of them the most common grade of ischemia was 3; percentile variations in the amplitudes of the waves could be seen in 100% of the newborns with clinical symptoms compared with 65% of those without. The total CPK and CPK-MB showed no differences between the newborns with perinatal hypoxia with or without cardiacal symptoms and another control group. The total CPK values showed significant differences (p < 0.05) from the ischemic electrocardiographic grades.