Actimeter and chronobiology in colics in young infants. Effect of two special diets

Abstract

Infantile colic modifies the behaviour of the child and the familial relationships. We established the following hypothesis: 1) the infantile colic is caused by cow milk proteins; 2) the infantile colic does not modifies the biological sleep/wake rhythm; 3) infants´s feeding with two different proteins hydolysate based formulae does not show differences in colic symptoms. The objectives are: 1) to know the influence of the colic on the infants behaviour; 2) to quantify the influence of the infantile colic on the sleep actigraphic pamateters; 3) to verify sleep/wake rhythm disturbs; 4) to study the influence of diet changes on clinic, actimetric and sleep rhythm variables. The design was elaborated through an interventional, prospective, longitudinal, concurrent and ramdomized study with two cohorts. The population consists of 40 children with infantile colic on cow milk formulae diet. Twenty of them were changed to two hydrolysated based formula (cases); and 20 continued on cow milk proteins (controls). The change of cow milk formulae for serum and soy hydrolysate formulae impoved symptoms; and serum hydrolysate got a more significative improvement than soy impovement. The exclusion of cow milk proteins from the diet, did not modify the parameters of sleep´s actimetry; nor the the sleep/wake rhythm parameters. The supression of cow milk of the diet of the breast feeding mother, improve infant´s symptoms; and either the changed by an hydolysate formula, in the botled feeding babies.